Survival analysis by tumor type revealed that EGFR amplifications in low-grade gliomas and head and neck cancers, CCNE1 amplifications in ovarian and uterine cancers, and CDK4 amplifications in sarcomas were associated with a low probability of OS, suggesting that only certain amplifications in particular tumor types are relevant in prognosis (Supplementary Figure S2e–t). This evidence concerns the gene EGFR and central nervous system cancer.