According to EORTC/MSG-criteria, in the presence of host factors (such as recent history of neutropenia, receipt of allogeneic stem cell transplant and prolonged use of corticosteroids), clinical criteria (including classical findings in the CT scan) and mycological criteria (cytology, direct microscopy, culture or GM-Antigen detection in serum or BAL as an indirect test), probable invasive aspergillosis had to be considered in all cases. This evidence concerns the gene PPP1R3A and Decreased total neutrophil count.