In the recently published European Thyroid Association Guidelines for the management of pediatric thyroid nodules and differentiated thyroid cancer (DTC), the authors recommend that the molecular gene analysis for the presence of BRAF V600E mutation in a fine-needle aspiration (FNA) specimen may be useful for diagnosis of PTC and therefore may be incorporated into the diagnostic work-up [21]. This evidence concerns the gene BRAF and differentiated thyroid carcinoma.