MKI67 and metastatic malignant neoplasm in the lymph nodes: Jee et al. investigated the expression of MTUS1 protein in lung adenocarcinoma and found that a low MTUS1 level was significantly associated with higher histological grade, lymphovascular invasion, lymph node metastasis, higher tumor stage, and higher Ki-67 proliferation index, and patients with a low MTUS1 protein level showed a poor prognosis [11].