TSPO and multiple system atrophy: Interestingly, some authors also compared the distribution patterns of TSPO radioligands in patients with PD and other neurodegenerative disorders; the observation that increased uptake of 11C-PBR 28 is present in the lentiform nucleus and cerebellar white matter in patients with MSA, while it is not appreciable in patients with PD, can be important for differential diagnosis [21].