TSPO and Parkinson disease: In a study aimed at the designation of an image-derived input function method for [18F]-DPA-714, Fang et al. observed that in PD patients, the TSPO genotype critically affects the Vt of this radioligand, with HAB subjects, showing increased uptake in [18F]-DPA-714 in terms of SUV in respect to MAB subject in the putamen, caudate, thalamus, hippocampus, frontal, temporal, occipital and parietal lobes.