Cancer Genome Atlas Research Network (TCGA) documents a plethora of genes associated with glioblastoma, including those observed with high mutations, such as isocitrate dehydrogenase (IDH), phosphatase and tensin homolog (PTEN), O6-methylguanine DNA methyltransferase (MGMT), tumor suppressor protein (TP53), epidermal growth factor receptor (EGFR), vascular endothelial growth factor (VEGF), and p16INK4a. This evidence concerns the gene PTEN and glioblastoma.