When comparing protein expression of key CmPn players within liver cancer subtypes, PAQR7, PGRMC1, and nPRs proteins were significantly differentially expressed only when comparing HCC to all other subtypes (Figure 4D,E and Supplementary Figure S5B), which was also observed in our preliminary TCGA analysis between HCCs and CCAs (Figure 3A). This evidence concerns the gene PAQR7 and hepatocellular carcinoma.