We observed significantly decreased protein expression for CCM1 (Figure 4(A-1),(A-2)), CCM3 (Figure 4(B-1),(B-2)), PAQR8 (Figure 4(C-1),(C-2)), PGRMC1 (Figure 4(D-1),(D-2)), and nPRs (Supplementary Figure S5B) in all liver cancer subtypes, compared to normal healthy liver tissues. The gene discussed is PAQR8; the disease is liver cancer.