We also observed newly dysregulated pathways, not observed in our breast cancer studies, including disruption of ECM–receptor interactions, complement/coagulation cascades, PPAR pathways, bile secretion, peroxisomes, sterol/cholesterol homeostasis, and ABC transporters (Figure 2(D-2)), which are known to influence liver tumorigenesis. This evidence concerns the gene ABCG2 and breast carcinoma.