In total, 48 C9orf72-associated ALS patients (C9orf72-ALS), 22 SOD1-associated ALS patients (SOD1-ALS), and 69 matched sporadic ALS patients (C9orf72-matchedsALS, n = 48; SOD1-matchedsALS, n = 21) were included, with a median age of 59 years (range, 29–84 years). Here, C9orf72 is linked to amyotrophic lateral sclerosis.