FOXP3 and hematocrit: The association of the functional SNPs of the FOXP3 gene (−3499A/G, −3279C/A, and −2383C/T) with the prognosis of AITD was also evaluated, and it was found that the −3279CA genotype was more frequent in patients with GBD in remission than in patients with intractable GBD, and that the −2383CC genotype was more frequent in patients with severe HT than in those with mild HT [141].