TNK2 and acute myeloid leukemia: As opposed to statistically significant upregulation in adrenocortical carcinoma, glioblastoma, skin cutaneous melanoma, thyroid, and endometrial cancer, TNK2 expression is downregulated in acute myeloid leukemia (AML), pancreatic cancer, and pheochromocytoma compared to the corresponding healthy tissues (Figure 5B).