Moreover, Li J. et al. [6] reported that a 15-year-old boy with Duchenne muscular dystrophy underwent hypotension following the administration of the angiotensin-receptor/neprilysin inhibitor sacubitril/valsartan, indicating that the boy could not even tolerate a small dose of the anti-hypertension drug. Here, MME is linked to Duchenne muscular dystrophy.