We observed the activation of the cholesterol biosynthesis, LXR/RXR and PPAR signaling pathways (Figure 2C and Figure S3); and the repression of the sirtuin, matrix metalloprotease, acute phase response, osteoarthritis, hepatic fibrosis and TGFβ signaling pathways (Figure 2B and Figure S3). This evidence concerns the gene PPARA and Hepatic fibrosis.