Histological comparison of the lungs collected from mice injected with JEG-3 Sh CTL or JEG-3 Sh NLRP7 showed that tumor development was observed in 71% of lungs collected from the JEG-3 Sh CTL group versus only 14% of lungs from the JEG-3 Sh NLRP7 group. The gene discussed is NLRP7; the disease is neoplasm.