For the four proteins that differed between PCOS subjects and control women (ApoE, ApoM, C3, and HCFII), correlations with age; BMI; insulin resistance (HOMA-IR); testosterone; and circulating levels of TG, cholesterol, HDL-C, LDL-C, and CRP were performed. The gene discussed is APOE; the disease is polycystic ovary syndrome.