CTLA4 and intrahepatic cholangiocarcinoma: For intrahepatic cholangiocarcinoma the following variables were included in the multivariate model: Tumor_CD8_PD-L1_PD-L2, Tumor_CD8_PD-L2, Tumor_CD4, Tumor_CD4_ICOS_TIGIT, Tumor_CD4_TIGIT, Tumor_CD4_TIGIT_CTLA-4, Tumor_CD8_ICOS, Tumor_CD8_ICOS_TIGIT, Tumor_CD8_ICOS_CTLA-4, Liver_CD8_PD-1_PD-L1, Liver_CD68_PD-1_PD-L1, Liver_CD4_CTLA-4, Liver_CD8_CTLA-4, Liver_CD4_TIM-3, Liver_CD8_TIM-3.