A common thread throughout those reports is that elevated expression of DCLK1 promotes pluripotency of cancer stem cells and epithelial-to-mesenchymal transition (EMT) in a kinase-dependent manner [27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46]. The gene discussed is DCLK1; the disease is cancer.