TLR6 (Figure 5B and Supplementary Figure S2G, respectively) and TLR7 (Figure 5C and Supplementary Figure 2H, respectively) were significantly overexpressed in infection-derived EVs compared to control-derived EVs, while TLR3 (Figure 5A and Supplementary Figure S2F, respectively) was expressed but significantly unchanged within EVs. The gene discussed is TLR7; the disease is infection.