Finally, when we evaluated the expression of cytokines IFN-γ, IL-17, and IL-10 through flow cytometry, we noted that stimulation with STAg and αCD3αCD28 did not increase or decrease the capacity to express cytokines in any of the groups, which indicates that the use of immunomodulating medication, whether synthetic or biological, still allows the response to be similar to that observed in individuals without autoimmune disease, such as those who composed the CG. The gene discussed is IL17A; the disease is autoimmune disease.