However, it is known that in individuals with AIDS, who have an immunosuppression that is much more pronounced than the immunosuppression caused by DMARDs used by patients with autoimmune diseases, the risk of neurological disorders triggered by the reactivation of tuberculosis is much greater than the risk of attacks caused by neurotoxoplasmosis; therefore, while tuberculous meningitis is associated with CD4+ levels below 400/mm3, toxoplasmosis is associated with CD4+ levels below 200/mm3 [53]. Here, CD4 is linked to nervous system disorder.