Patients with tumor recurrence at 1-year follow-up showed statistically significant elevated follow-up chitotriosidase values (with 4.3 ng/mL [4.1 to 4.7], n = 8 vs. without 1.8 ng/mL [0.9 to 4], n = 34; Mann-Whitney test: p-value = 0.0282) and neopterin (with 3.1 ng/mL [2.3 to 6.2], n = 8 vs. without 1.6 ng/mL [1.3 to 2], n = 34, Mann-Whitney test: p-value = 0.0003) than those without recurrence. This evidence concerns the gene CHIT1 and neoplasm.