Antinuclear antibodies (ANA) consist of various autoantibodies targeting nuclear protein and cytoplasmic cell components, including anti-dsDNA, anti-ribonucleoprotein (RNP), anti-Sm, and anti-Ribosomal P (Rib-P) antibodies, and are detected in ~95% of SLE patients (Table 2) [24]. This evidence concerns the gene BTG3 and systemic lupus erythematosus.