KMT2A and acute lymphoblastic leukemia: The current classification recognizes KMT2A-r acute lymphoblastic leukemias as B lymphoblastic leukemia/lymphoma with t(v;11q23.3) (KMT2A-r) with any fusion partner [7], whereas the updated International Consensus Classification (ICC) of B-acute lymphoblastic leukemia (B-ALL) and T-acute lymphoblastic leukemia (T-ALL) recognizes KMT2A-r ALL as B-ALL with t(v;11q23.3)/KMT2A rearranged and B-ALL KMT2A rearranged-like (in this case as a provisional entity—with frequency <1%, including some with HOXA fusions) [8].