Over-activation of YAP1/TAZ through the aberrant regulation of Hippo kinases has been noted in many types of tumors and is associated with the acquisition of malignant traits, including resistance to anticancer therapies, maintenance of cancer stem cells, distant metastasis [1,2,3], and in prostates, AI adenocarcinoma progression [5,6]. The gene discussed is YAP1; the disease is adenocarcinoma.