Among the anti-TTN antibody-positive MG patients, we observed the following: patients with type A/AB thymomas had lower TTN and AIRE expression levels, which were associated with higher levels of NEFM; patients with type B1/B2 thymoma also had lower levels of TTN and AIRE; and patients with B3/B3 mixed thymomas had higher levels of NEFM, which was associated with the AIRE decrease, compared to seronegative non-MG patients having the same thymoma type (Figure 7b). The gene discussed is TTN; the disease is myasthenia gravis.