In our present investigation, analyzing a larger patient sample than in our previous study [12], we aimed to investigate the relationship between the intensity levels of protein expression (GHRH-R, Hsp90, Hsp16.2, p-Akt and SOUL) in pretreatment tumor samples, as well as the 10-year overall survival (OS) and time to metastasis rates. The gene discussed is AKT1; the disease is neoplasm.