SNCA and Parkinson disease: The 6-OHDA model shares a common failing with many other animal models of PD as it does not lead to the formation of the pathological hallmark of PD, the Lewy body, that contain ubiquitinated proteins such as α-synuclein [73]; therefore, the change in glutamate receptor levels in our research, especially AMPA receptors, is associated with dopaminergic degeneration seen as positive correlation between TH and pAMPAR levels.