As shown in Supplementary Figure S2A,B, when the IL-6 levels were compared between the SKBR3 and HCC1954 cells, representative breast cancer cell lines that are sensitive and resistant to TRZ, respectively [24], IL-6 expression was significantly higher in the HCC1954 cells compared to those of the SKBR3 cells. This evidence concerns the gene IL6 and breast carcinoma.