CCL2 and gout: In addition, the enhanced production of chemokines—including IL-8 (C-X-C motif chemokine ligand 8 (CXCL8)) [6], macrophage inflammatory protein (MIP)-1α (C-C motif chemokine ligand (CCL3)) [7], MIP-2/CXCL2 [7], monocyte chemoattractant protein-1 (MCP-1) [8], and CXCL16 [9]—has been found to be associated with the pathogenesis of uric acid-induced inflammation in gouty arthritis.