NFKB1 and acute respiratory distress syndrome: Exosomal miR-92a-3p from LPS-treated AECs suppresses PTEN expression before activating the nuclear factor-kappaB (NF-κB) signal, which boosts pro-inflammatory factor (e.g., IL-1β, IL-6, and TNF-α) release in AMs, eventually resulting in lung inflammation and ALI [107].