Biomarkers such as urinary albumin-creatinine ratio (UACr), neutrophil gelatinase-associated lipocalin (NGAL), kidney injury molecule-1 (KIM-1), insulin-like growth factor-binding protein-7 (IGFBP-7), gelsolin (GSN), liver-type free-fatty-acid-binding protein (L-FABP), and interleukin-18 (IL-18) have been regarded as early predictors of kidney injury [19,20,21,22]. The gene discussed is LCN2; the disease is injury.