Acromegaly remission was considered off-medication GH levels (nadir GH < 0.4 μg/L during an oral glucose tolerance test, and/or random GH < 1.0 μg/L) or normalized IGF-1 (<1) at 6-month follow-up after surgery by Qiao et al. to forecast response of functioning pituitary adenomas (FPA) to surgery [18]. The gene discussed is IGF1; the disease is pituitary gland adenoma.