By using this technique, researchers found greater TSPO binding within the dorsal caudate, orbitofrontal cortex, thalamus, ventral striatum and dorsal putamen of 20 OCD patients compared to matched healthy controls, indicating that the aberrant inflammatory processes in OCD might extend beyond the basal ganglia to include the cortical-striatal-thalamic circuits (CSTC) [46,47]. The gene discussed is TSPO; the disease is Compulsive behaviors.