From the KEGG, they were strongly related to the cancer-related pathways (e.g., cell cycle, ECM receptor interaction, and p53 and JAT-STAT signaling pathways) and immune-related processes (e.g., antigen processing and presentation, and cytokine–cytokine receptor interaction), and negatively related to the MAPK, Wnt, and ERBB signaling pathways. This evidence concerns the gene TP53 and cancer.