KCTD1 and rectum adenocarcinoma: Since the upregulation of β-catenin expression and the consequent activation of the WNT/β-catenin pathway have been correlated to an increase in colorectal cancer [24], we evaluated KCTD1 mRNA expression levels in patients with colon adenocarcinoma (COAD) and rectum adenocarcinoma (READ) using data reported in the Cancer Genome Atlas (TCGA).