KCTD1 and colorectal adenocarcinoma: The interplay between KCTD1 knockdown and the WNT/β-catenin pathway was investigated using the human colorectal adenocarcinoma cell line, SW480 (https://web.expasy.org/cellosaurus/CVCL_0546 accessed on 1 February 2023), in which the protein is significantly expressed [22].