WWOX and neoplasm: Initially recognized as a putative tumor suppressor in breast cancer, the WWOX gene is now in the spotlight for its possible role in, e.g., central nervous system (CNS) and related neurological disorders [2,9,32,40,41,42,43,44,45,46] such as WWOX-related epileptic encephalopathy (WOREE), for which a WWOX gene therapy was recently suggested as a proof-of-concept [47].