In agreement with these data, FGFBP1 has been shown to be significantly upregulated in the hemolytic uremic syndrome associated with human immunodeficiency virus (HIV-HUS), which is characterized by endothelial damage and microcystic tubular dilation [34,35]; furthermore, the inhibition of FGFBP1 was shown to be beneficial in preventing brain vessel damage triggered by acute kidney injury [32]. The gene discussed is FGFBP1; the disease is acute kidney injury.