For instance, miR-338-3p can promote angiogenesis in hepatocellular carcinoma (HCC) by targeting MACC1, b-catenin, and VEGF; MACC1 is positively correlated with VEGF in cholangiocarcinoma [16] and angiogenesis in cervical cancer [41]. This evidence concerns the gene VEGFA and hepatocellular carcinoma.