The up-regulated DEGs were mainly enriched in the neuroactive ligand-receptor interaction, amoebiasis, axon guidance, proteoglycans in cancer, Wnt and MAPK signaling pathway; while the down-regulated DEGs were mainly enriched in chemical carcinogenesis, fatty acid elongation, fatty acid metabolism, Jak-STAT signaling pathway and so on. Here, SOAT1 is linked to amebiasis.