The induction of anti-oxidative factors (Figure 4) may overall not rescue the cells from zinc deficiency-induced apoptosis, In summary, our data indicate that zinc deficiency increases the expression of CAT, SOD, IGF-I and IGF-II in SF epithelial cells (Figure 4 and Figure 5), which remains to be tested on the protein and enzyme activity level. The gene discussed is CAT; the disease is Zinc deficiency.