Increased concentrations of insulin and HOMA-IR levels observed in women with PCOS were positively correlated with oxidized glutathione concentrations (r = 0.418, p = 0.001; r = 0.405, p = 0.002, respectively) and negatively correlated with R-index values (r = −0.304, p = 0.003; r = −0.380, p = 0.004, respectively). This evidence concerns the gene INS and polycystic ovary syndrome.