LOX and metabolic dysfunction-associated steatotic liver disease: On the contrary, oxylipins derived from docosahexaenoic acid (DHA) through the LOX pathways, such as 17DoHE and RvD2, are present in the plasma of all patients at a similar concentration, although MaR1 plasma levels, also derived from DHA, are increased in severe NAFLD patients compared to the other NAFLD stages.