The ω-3 fatty acid-supplemented endotoxemic rats in the therapeutic and prophylactic protocols showed improved liver function with decreases in the endotoxemia-induced increased blood levels of the liver dysfunction markers alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TBIL), and gamma-glutamyl transferase (GGT) (Figure 7A–D, middle left panel), compared to sham-supplemented endotoxemic rats (Figure 7A–D, left panel). Here, GPT is linked to serum lipopolysaccharide activity.