In this study, we studied the neuroprotective potential of AD−1 small molecule in in vivo scopolamine-induced memory dysfunction by evaluating the potential mechanisms involved in changes in motor activity, the spatial memory function using Y-maze and MWM tests as well as AChE activity, biochemical, and Western blot changes in the hippocampus and cerebral cortex of AD mice. Here, ACHE is linked to Alzheimer disease.