HDAC9 and early-onset autosomal dominant Alzheimer disease: In neurodegenerative diseases, HDAC inhibitors were found to improve the redox balance and attenuate neuronal degeneration in Huntington’s disease [65] and amyotrophic lateral sclerosis [66] mouse models and in Alzheimer’s disease-like pathological changes in SH-SY5Y neuroblastoma cells [67].