The injection of Margatoxin (MgTx), an inhibitor of Kv1.3 (but also of Kv1.1 and Kv1.2 [15]), directly into the xenograft of the A549 human lung adenocarcinoma cell line at 1 nM concentration, inhibited tumor growth in a nude mice model [16]. This evidence concerns the gene KCNA2 and neoplasm.