TP53 and cancer: According to research that agrees with our findings, AgNPs may have antitumor effects by inhibiting cell proliferation and inducing proapoptotic events through the p53, Bax/BCL-2 and caspase pathways [11], as well as by causing DNA fragmentation and altering cellular redox status in cancer models for cervical, breast, lung, nasopharyngeal, hepatocellular, glioblastoma and colorectal cancer [9].