Risk factors for persistent methicillin-resistant S. aureus (MRSA) bacteremia include liver cirrhosis, endocarditis, bone and joint infections, metastatic infection, septic shock, complicated bacteremia, C-reactive protein level ≥ 10 mg/dL, diminished susceptibility to vancomycin, vancomycin heteroresistance, accessory gene regulator dysfunction, and low-level in vitro resistance to thrombin-induced platelet microbicidal proteins [14,15,16]. This evidence concerns the gene CRP and bacterial infectious disease with sepsis.