APOBEC3s can also inhibit cell death via multiple mechanisms: APOBEC3G was shown to inhibit anoikis via Akt activation in pancreatic cancer, and APOBEC3B may decrease cell death in gastric cancer by inhibiting PDCD2 function and lowering ATM and Chk1/2 activity [38, 49]. The gene discussed is APOBEC3B; the disease is gastric cancer.