APOBEC3G and pancreatic neoplasm: APOBEC3s can also inhibit cell death via multiple mechanisms: APOBEC3G was shown to inhibit anoikis via Akt activation in pancreatic cancer, and APOBEC3B may decrease cell death in gastric cancer by inhibiting PDCD2 function and lowering ATM and Chk1/2 activity [38, 49].