Furthermore, it can reduce the expression of MHC antigen-presenting cells, maintain lymphocyte infiltration in the tumor tissue, and form a new type of Th2 infiltrating lymphocytes in the tumor tissue (tumor-infiltrating lymphocytes, TIL) cells, forming TIL–IL-4–IL-10 “Th2 cycle” [58], and could promote the immune escape of tumors [59]. Here, IL4 is linked to neoplasm.