There was increased expression of fibronectin in the ILD subjects compared to the control subject as measured by IHC for DAB fibronectin-EDA, Control Vs ILD, 54.63 ± 19.6 vs 516.2 ± 115.6, P value < 0.0001 (Fig. 2A, B). This evidence concerns the gene FN1 and interstitial lung disease.