MTR and neoplasm: On days 7 and 10 after tumor cell implantation, engineered macrophages were infused intravenously as shown in Fig. 6A. On day 14, the mice were sacrificed, and we found that the number of metastatic nodules in the lungs of mice treated with CAR-Ms and M1-polarized CAR-Ms was significantly reduced (Fig. 6B, C).